Effect of 2-hydroxy-4-methoxy benzoic acid isolated from Hemidesmus indicus on erythrocyte membrane bound enzymes and antioxidant status in streptozotocin-induced diabetic rats
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منابع مشابه
Effect of 2-Hydroxy-4-methoxy Benzoic Acid Isolated from Hemidesmus indicus on Erythrocyte Membrane Bound Enzymes and Antioxidant Status in Streptozotocin-induced Diabetic Rats
In the present study, the effect of 2-hydroxy-4-methoxy benzoic acid isolated from roots of Hemisdesmus indicus on the erythrocyte membrane bound enzymes and antioxidant status in streptozotocin-induced diabetic rats was investigated. The streptozotocin-induced diabetic rats were treated with 2-hydroxy-4-methoxy benzoic acid (500 μg/kg/day) for 7 weeks by oral intubation and compared with glibe...
متن کاملEffect of 2-hydroxy 4- methoxy benzoic acid isolated from the roots of Hemidesmus indicus on blood glucose and tissue lipid peroxidation in streptozotocin-induced diabetic rats
Effect of 2-hydroxy 4methoxy benzoic acid isolated from the roots of Hemidesmus indicus on blood glucose and tissue lipid peroxidation in streptozotocin-induced diabetic rats M. Gayathri, K. Kannabiran* *School of Biotechnology, Chemical and Biomedical Engineering,VIT University, Vellore-632 014, Tamil Nadu, India. For correspondence:Dr. K.Kannabiran,Professor, School of Biotechnology, Chemical...
متن کامل2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
Protective effect was evaluated in streptozoticin (STZ)-induced diabetes rats. 2-Hydroxy 4-methoxy benzoic acid (HMBA) was isolated from the roots of Hemidesmus indicus and administered (500 microg/kg body weight) orally for 7 weeks to STZ-induced diabetic and non-diabetic rats to study its effect on protein metabolism, serum electrolytes and on liver and kidney lipid peroxides. Oral administra...
متن کاملSYNTHESIS OF 8-HYDROXY-6-METHOXY- 3-UNDECYLISOCOUMARIN AND 2-HY DROXY - 4-METHOXY-6-(2-OXOTRIDECYL) BENZOIC ACID
Straightforward conversion of (+)-6,8-dimethoxy-3,4-dihydro-3- undecylisocoumarin (3) to the title isocoumarin was carried out. Hydrolytic ring opening of (3) afforded the hydroxy acid (4) which was immediately oxidized to keto acid (5) using chromic acid, Cyclodehydration of (5) afforded the 6,8- dimethoxy-3-undecylisocoumarin (6) which on selective demethylation of 8- methoxy group furni...
متن کاملEffect of morin on glycoproteins and membrane bound enzymes in streptozotocin-induced diabetic rats
This study investigated the effect of morin on membrane bound enzymes and glycoproteins in normal and streptozotocin (STZ)-induced diabetic Wistar rats. Diabetes was induced in rats by an intraperitoneal injection of STZ, dissolved in citrate buffer (0.01 M, pH 4.5) and injected to overnight fasted rats with a dose of STZ 50 mg/kg. Morin was dissolved in carboxy methyl cellulose (CMC) at a dose...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2012
ISSN: 0250-474X
DOI: 10.4103/0250-474x.108438